改善人脑感受的神经模式调制
未来是大哥的共产主义世界,在一个巨大的监控中心有许多不同的专业部门,人们可以从快乐中心植入快乐,从自由中心下载自由,从民主中心体验民主... 小粉红们只要信大哥就有了一切。
以下是一篇 2021年 1月18日出现在《自然 医学》 的文章题目和摘要:
对抑郁患者脑内颅底神经刺激的状态响应
State-dependent responses to intracranial brain stimulation in a patient with depression
作者: Katherine W. Scangos, Ghassan S. Makhoul, Leo P. Sugrue, Edward F. Chang & Andrew D. Krystal
自然 医学 2021 引用此文
Nature Medicine (2021)Cite this article
摘要
Abstract
对于严重抑郁症,深脑刺激是一种有希望的疗法,但是在随机实验中缺少效果,这对解剖对象提出了问题。我们为一位深度抑郁的患者植入了颅内电极并且系统的评估了对焦点电神经调制的准确响应。我们发现对精心设置的不同情绪剧目有迅速发生的反应,可以复制,并且和环境和状态相关。结果提供了概念证实,可以有个人化的,芯片设置的心理学医治。
Deep brain stimulation is a promising treatment for severe depression, but lack of efficacy in randomized trials raises questions regarding anatomical targeting. We implanted multi-site intracranial electrodes in a severely depressed patient and systematically assessed the acute response to focal electrical neuromodulation. We found an elaborate repertoire of distinctive emotional responses that were rapid in onset, reproducible, and context and state dependent. Results provide proof of concept for personalized, circuit-specific medicine in psychiatry.
以下是一篇 2021年 1月18日出现在《自然 医学》 的文章题目和摘要:
对抑郁患者脑内颅底神经刺激的状态响应
State-dependent responses to intracranial brain stimulation in a patient with depression
作者: Katherine W. Scangos, Ghassan S. Makhoul, Leo P. Sugrue, Edward F. Chang & Andrew D. Krystal
自然 医学 2021 引用此文
Nature Medicine (2021)Cite this article
摘要
Abstract
对于严重抑郁症,深脑刺激是一种有希望的疗法,但是在随机实验中缺少效果,这对解剖对象提出了问题。我们为一位深度抑郁的患者植入了颅内电极并且系统的评估了对焦点电神经调制的准确响应。我们发现对精心设置的不同情绪剧目有迅速发生的反应,可以复制,并且和环境和状态相关。结果提供了概念证实,可以有个人化的,芯片设置的心理学医治。
Deep brain stimulation is a promising treatment for severe depression, but lack of efficacy in randomized trials raises questions regarding anatomical targeting. We implanted multi-site intracranial electrodes in a severely depressed patient and systematically assessed the acute response to focal electrical neuromodulation. We found an elaborate repertoire of distinctive emotional responses that were rapid in onset, reproducible, and context and state dependent. Results provide proof of concept for personalized, circuit-specific medicine in psychiatry.
