如何评价印度科学家在武汉肺炎病毒中发现疑似艾滋病毒基因插入的研究?
有爆料称，印度科学家刚刚在武汉肺炎病毒中发现了类似艾滋病毒的基因插入，而这种情况在任何其他冠状病毒中没有发现过。他们暗示这种有可能是人为设计出来的，有人立即想起那个得了病并说用抗艾滋药物治好了的国家组专家王广发。有没有相关专业的葱友科普一下真实性。
Abstract:
We are currently witnessing a major epidemic caused by the 2019 novel coronavirus (2019-
nCoV). The evolution of 2019-nCoV remains elusive. We found 4 insertions in the spike
glycoprotein (S) which are unique to the 2019-nCoV and are not present in other coronaviruses.
Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary
amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute
the receptor binding site.
The finding of 4 unique inserts in the 2019-nCoV, all of which have
identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature.
This work provides yet unknown insights on 2019-nCoV and sheds light on
the evolution and pathogenicity of this virus with important implications for diagnosis of this virus.
论文下载地址：
https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1.full.pdf
Abstract:
We are currently witnessing a major epidemic caused by the 2019 novel coronavirus (2019-
nCoV). The evolution of 2019-nCoV remains elusive. We found 4 insertions in the spike
glycoprotein (S) which are unique to the 2019-nCoV and are not present in other coronaviruses.
Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary
amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute
the receptor binding site.
The finding of 4 unique inserts in the 2019-nCoV, all of which have
identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature.
This work provides yet unknown insights on 2019-nCoV and sheds light on
the evolution and pathogenicity of this virus with important implications for diagnosis of this virus.
论文下载地址：
https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1.full.pdf
他给的那个论文网址是正规的科研站，并且他有蓝标认证，因此我认为这个说法至少有胆经得起挑战。就好比开源软件，你放得出来，有恶意后门的可能性几乎不存在。这个病毒到现在应当有的一个共识就是，不太可能是自然界生成的，而只能是实验室人为设计出来的，只不过现在似乎全球尚没定论是哪个邪恶的国家的实验室而已，但也许公布出来的时间不会晚吧。
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